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That was the most interesting aspect talking to guys that went through that game. Anyone that takes 30mg x 3 daily..... Yeah you're gonna get hooked. Then cold turkey one day bc well politics. One will switch to heroin, and since heroin is super expensive now. You switch to cartel knock off perc 30's doped w/fentanyl... Throw in the fact that they wholesale via the cartel at a dollar a pill.... Hell a lot cheaper than big Pharma prices... DEA. Beautiful organization... |
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Substituting LSD for opiates as a strategy for pain control is a great plan if you want to go out of business while making national news.
Ketamine (dissociative effects comparable to LSD) has its place but is not a great plan A, B and C unless the situation is extremely dire and then only until it improves enough to give other meds including opiates. There are efforts toward establishing opiate-free environments but the back-up plan for pain control in those places is generally opiates because they are reliable. |
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However, they want to die. |
You are correct about benzos and booze, also true of opioids and booze
Pretty easy for someone to have a heart attack going through opioid withdrawal. One of the reasons you don't let your patients go through it on purpose. https://pubmed.ncbi.nlm.nih.gov/25024850/ |
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Think receptors and big picture.... |
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When I tried Vicodin it made me want to lay on the sofa and do nothing all day. I wasn't in pain, but I wasn't getting anything done. The thing was, if I just laid on the sofa I wasn't in pain anyway, so I didn't need a drug if that was my goal. My back and hip pain is excruciating in the morning and taking a Tramadol helps me get through my stretches and strengthening exercises and my walk. Before I started using it I couldn't walk 200 yards and I was getting worse. Now I'm walking 2 1/2 miles a day plus half an hour of stretches and strengthening exercises. After I get over the morning hump I'm good for hours. As my doc said, "Motion is medicine" and a Tramadol lets me get the daily motion going. Of course if you are using it to help relieve the cramps from sitting on the sofa all day, it's not your long-time solution. |
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I had a knee replacement several years ago.
I was given Hydrocodone and used it liberally, until I had a reaction and felt I was going to die. My wife was out of the country, and I felt so bad that I contemplated calling an ambulance. But I got over it and just stopped taking them that day. It is good used properly, under supervision, as all drugs are. But the opportunity for abuse is so high I can see how people get sucked into it and ruin their lives. |
I like oxytocin....
In the barracks i had a **** bag roomie. ps refused to let me change rooms. Anyways. My roomie had his acl done. Con leave denied. So he's taking his hydrocodone and crushing it in 10 dollar bills and snorts lines right on that skillcraft desk they all have. Next script he gets oxytocin. The pharmaceutical company changes the binder so they don't crush but smear into a waxy residue... it was a sign of relief until i got out of that room..... |
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Whaaaa, "opiate" receptors are different than 5ht** receptors?....
/s Find a copy of that journal on sci hub and lmk if you have any questions on the "dissociative"... |
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One of the absolute BIGGEST failures of biomedical research for the last 30-40 years is the total inability to come up with a non narcotic solution to chronic ( and acute pain) that is non addictive and has none of the GI and CNS side effects of narcotics,. Compared to our huge advances in many diseases, this is an abject failure both of focus and expertise to take it on... ( notwithstanding political will) The major pain signal transduction pathways, receptors, nerve efferent and afferents have been well known for 50 years! Big pharma is to blame also as they would rather one of their most reliable cash cows to not go away.... its astounding
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There's nothing cryptic in that response... Now. Fly fly fly Fly fly fly |
So for some on ppot that still have some firing dendrites.
Sci hub is an open source doi search engine for scientific journals. |
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