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				Originally posted by Sebring77  
The one thing that stands out to me is statements such as "I don't know if they make one, but that would be a good choice...." 
This re: 380 Glocks and High Standard pistols. (Btw-Yes they make them-no you can't have one in N.A. and Yes they make them again but they're different than the old ones-sorta) 
 
Anyway- this is a very important issue. PBS911 has not provided nearly enough info for an answer.  PBS911, and anyone else considering a firearm of any type needs to confer with a real expert on this and make a selection based on that expert's informed advice. 
 
Don't get me wrong-Lots of you provided good info that is always true-practice, instruction, etc. Although I'm still wondering about that .22 thing because it's quiet:rolleyes: . 
			
			 
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Isa actually wrote: "I don't know if they're STILL made" 
 
The advantage of the .22 especially for a beginner is ease of use and that one does not become gun shy as one might starting with a larger calibre.  
 
22 for defensive use?  I seem to remember experts such as Dean Grennel and Massad Ayoob amongst others suggesting it under certain conditions - such as for a novice where it may help a lot with placement - better a hit with a 22 than a miss with a 44.  
 
As you rightly say: Limited information and, Confer with an expert.  The difficult part is identifying a true expert who really understands the individual requirements and interprets them in the light of the individual's profile.  eg In my case I am uncomfortable shooting revolvers and the Beretta 92 does not fit my hand - neither would be a good choice for me.
 
9mm stopping power has been a discussion point for years, it is generally accepted that the 357 and 45 acp are superior but 9mm loaded to NATO spec will certainly perform a bit better than the usual loading and  it is usually hardball that is used for comparisons.  If loaded with hollowpoints, (assuming your auto won't choke on them) the 9mm  will perform better than expected.   Performance will again improve with some of the more modern rounds - I'm not sure if these are freely available in the US to non-police.  I think it was Evan Marshall or Leroy Thompson that did lots of comparisons on stopping power, I'm afraid I haven't really kept up with the subject as my interest nowadays is mostly target.  Ultimate stopping power indoors is probably a shotgun with a short barrel.
 
My own personal choice is 7.65 parabellum (anachronistic I know).  
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