Ac question
 

Would moisture in an AC system cause the high side pressure to spike super high long before a full charge is in the system? I replaced the condensor, ( massive leak), removed and flushed the fixed orfice pipe, flushed out the lines and evaporator, and vacumed the hell out of this system. But when I am trying to fill it right after I get about half of the reccomended charge in , the high pressure starts to climb to well over 400 lbs. This is at about 80 deg ambient temp, and plenty of air passing over the condensor. The system was left opened for about a week with no plugs to cover the lines/ evap etc... I am assuming I will need to replace the drier , and vacum the piss out of it again.
A clogged orfice tube will cause lower pressures on the high and low side , correct?
I would have replaced it already, but it is part of the liquid line, which is on back order right now.

A clogged orifice tube or restriction will create high pressures on the high and low pressure on the low side.

IIRC, non-condensibles in the system will show up via fluctuations in pressure as the moisture moves through the system and changes physical state. One check is via temp-pressure curves. Let the system sit and allow temperature of the system to stabilize. Check temperature of a refrigerant line and refer to temp-pressure chart of the refrigerant. If you have moisture, the pressure will read higher.

Purge with nitrogen and vacuum. You shouldn't have much moisture with a nitrogen purge. You can triple purge as an extra measure.

Personally, I think you have a restriction, perhaps in the orifice.
jurgen

If you have moisture in the system you won't be able to pull a decent vacuum.
How are you determining the vacuum level is OK (under 500 microns)?
Is this an automotive system or ?
You may have a blockage though moisture can block your expansion device and create a blockage.

My money is on the dryer. If left open for a week it has picked up a lot of moisture.

My bet is on the liquid line. The Dodge or Jeep liquid lines are not nearly as scarce as the compressor, however one liquid line is somewhat hard to find.. I have a ton of liquid lines. What's the year, make, model, engine size?

Don't rule out the condenser, I have seen a few that don't have the same cooling capacity (rows), and if it is a micro tube condenser, it is plausible that when welding the ends to the rows the tubes became restricted.

When the system was under vacuum, it would have boiled the moisture out of the drier/accumulator.

no, a clog will cause the hi side to go higher (like 400psi) and the low side to go low or even into a vacuum.