[Purrybonker]

Sounds like an "endurance" type fit might work for you.

Trek Domane, Ridley Fenix, Specialized Roubiax? These are bike meant for long days in the saddle. You can play with stems, etc to get a bit more aggressive if you like. I'm not familiar with Bianci, can't speak to that.

With those climbs/downhills you should go disc. More maintenance (my pads seems to be good for about 4 to 5,000 km, but I don't climb as much as you do) but it's the only way to go, really, imho.

Keep your rims shallow, none of that deep areo stuff. Shallow rims climb better and you won't get shoved around in fast downhill runs with pushy crosswinds.

As with your Porsche, add lightness - carbon frame, stem, bars, rims, all can be had.

Groupsets are a matter of taste really, Shimano 105 is all that's needed and works like a charm but, geezus those Di2's and SRAM etap are sweet. But the electronic stuff would probably push you out of your price range.

Pick your cassettes/cranksets to suit your preference - this is an important way to make the bike work best for you.