I haven't had to deal with it directly but my ex wife going through it right now.
My kids are trying to do the best they can. They love their mum but she's being really awful right now.
HRT (hormone replacement therapy) may be an option but I've also heard negative things about it.
I would encourage you to hang in there. At some point she'll come out the other side and things should return to normal.
FWIW: My much younger GF has "episodes" every couple of months or so. She's only 47 but IMO she's driven by her hormones. When she gets like that I just keep my distance for a while and let her contact me. (One of the benefits of not letting her move it.

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