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Zeke's Avatar
 
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Quote:
Originally Posted by Craig T View Post
LOL...Where did you get that information? Celecoxib (sulfonamide moiety) There are a few non-active ingredients as filler and absorption aids e.g gelatin and lactose.

Celebrex has been a miracle drug for me. It's not cheap, but its a lot better than being addicted to opiates. I've been taking it for three years with great success. About every 8 months I give my stomach a break for two weeks, but Celebrex is the easiest on your stomach of all the NSAIDs. I'm stockpiling it while my insurance covers it.

Consensi is available since May '18. valdacoxib (Bextra) was withdrawn from the market as was rofecoxib (Vioxx). Lumiracoxib and Etoricoxib (Arcoxia) are sold in other countries. That shows that Celebrex is not totally unique.

There are also many more natural substances that can inhibit COX enzymes but I'll leave it at that.


flavonoids, fish oils, vitamin D

Old 08-09-2018, 01:32 PM
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Quote:
Originally Posted by Zeke View Post
Consensi is available since May '18. valdacoxib (Bextra) was withdrawn from the market as was rofecoxib (Vioxx). Lumiracoxib and Etoricoxib (Arcoxia) are sold in other countries. That shows that Celebrex is not totally unique.

There are also many more natural substances that can inhibit COX enzymes but I'll leave it at that.


flavonoids, fish oils, vitamin D
All due respect...You're obviously not someone dealing with the chronic everyday pain of degenerative joints. Something tells me plant metabolites and fish oil ain't going to ease my pain.

I do not however, believe "flavonoids" are quackery. I was involved in a study in the early 90's that showed the flavonoid Genistein (isoflavone from soy) being very effective at inhibiting angiogenesis in estrogen receptor and progesterone receptor (ER/PR) positive breast tumors. The company, Aeron Biotechnologies, sold me their cryo-bank of cytosol and paraffin breast cancer tissues and their diagnostic subsidiary to fund their focus on Genistien oncology applications. They've done well with it.
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Old 08-09-2018, 02:04 PM
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Years ago I read that Citrus pulp, especially oranges, was loaded with bioflavonoids.
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Old 08-09-2018, 05:21 PM
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Originally Posted by Craig T View Post
All due respect...You're obviously not someone dealing with the chronic everyday pain of degenerative joints. Something tells me plant metabolites and fish oil ain't going to ease my pain.

I do not however, believe "flavonoids" are quackery. I was involved in a study in the early 90's that showed the flavonoid Genistein (isoflavone from soy) being very effective at inhibiting angiogenesis in estrogen receptor and progesterone receptor (ER/PR) positive breast tumors. The company, Aeron Biotechnologies, sold me their cryo-bank of cytosol and paraffin breast cancer tissues and their diagnostic subsidiary to fund their focus on Genistien oncology applications. They've done well with it.
You haven't read many of my posts, Craig. I'm likely going in for shoulder replacement, (they want to do both) but my right shoulder is so painful that I have to sometimes use my left arm to get my right arm off the mouse and back to the keyboard.

I use Meloxicam and Voltaren gel and sometimes a lidocaine patch. For the left shoulder and the rest of my joints I try to eat sensibly with greens and fruit part of my daily diet. Also I haven't had any meat of any kind since 1984. Any.
Old 08-10-2018, 08:38 AM
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Also I haven't had any meat of any kind since 1984. Any.
Well, there's your problem.
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Old 08-10-2018, 08:52 AM
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Originally Posted by Zeke View Post
You haven't read many of my posts, Craig. I'm likely going in for shoulder replacement, (they want to do both) but my right shoulder is so painful that I have to sometimes use my left arm to get my right arm off the mouse and back to the keyboard.

I use Meloxicam and Voltaren gel and sometimes a lidocaine patch. For the left shoulder and the rest of my joints I try to eat sensibly with greens and fruit part of my daily diet. Also I haven't had any meat of any kind since 1984. Any.
Ouch Zeke!, I do apologize. I did not know that, and certainly know how you feel. Constant pain is very depressing. I also eat healthy greens and fruit, but do enjoy my steaks.

I had cortisone and lidocaine injections last week. They don't help much anymore. I agree with you that Celebrex is a risk long term, but I'm desperate and it helped for a long time.

My left elbow surgery is on Aug 29th, followed by the right elbow on Sept 12 when the left splint comes off. I sure hope it works. They say that it will...But surgeons make money cutting and will tell you anything you want to hear to get the billing.
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Old 08-10-2018, 05:15 PM
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After reading these stories (Zeke, Craig) I don’t feel so bad. I take naproxen for pain - that’s all. On a good day I can walk normally, other days i hobble around like a penguin. On bad days I walk like Grampaw on The Real McCoys. But I’m not in the kind of pain you describe.
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Old 08-10-2018, 08:14 PM
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Originally Posted by Craig T View Post
Ouch Zeke!, I do apologize. I did not know that, and certainly know how you feel. Constant pain is very depressing. I also eat healthy greens and fruit, but do enjoy my steaks.

I had cortisone and lidocaine injections last week. They don't help much anymore. I agree with you that Celebrex is a risk long term, but I'm desperate and it helped for a long time.

My left elbow surgery is on Aug 29th, followed by the right elbow on Sept 12 when the left splint comes off. I sure hope it works. They say that it will...But surgeons make money cutting and will tell you anything you want to hear to get the billing.
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Originally Posted by wdfifteen View Post
After reading these stories (Zeke, Craig) I don’t feel so bad. I take naproxen for pain - that’s all. On a good day I can walk normally, other days i hobble around like a penguin. On bad days I walk like Grampaw on The Real McCoys. But I’m not in the kind of pain you describe.
Well, it's not unusual for us guys to have worn things out. I manage but it's a controlled management. For instance, I might as well throw every hammer I have in the trash. These are not friendly tools for me anymore. OTOH, I was on the roof this morning changing out a blower fan for my roof top air conditioning unit and spent the afternoon outside welding a project for a customer in this heat.

Pain sucks but the best thing is to work around it as much as you can, or try to ignore it. Pain is life at an older age and life can be a pain. I choose the former and just get a little more tough.

You guys remember when y'all kept at me as being the curmudgeon? Well, that was a time when all this was coming down on me. Fvvk all that. Now I'm glad to wake up in the morning. After that, POC.
Old 08-10-2018, 09:15 PM
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My own method of pain control - mount the sill bib at 3' and the hose reel at 5' so I don't have to bend over to use them. My shoes are no longer on the floor in the closet, I put them on a shoulder-level shelf.

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Old 08-13-2018, 09:44 AM
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Quote:
Originally Posted by Zeke View Post
I use Meloxicam and Voltaren gel and sometimes a lidocaine patch. For the left shoulder and the rest of my joints I try to eat sensibly with greens and fruit part of my daily diet. Also I haven't had any meat of any kind since 1984. Any.
Zeke.. No expert in your particular aches & pains but just chiming in on Voltaren. That molecule is the only thing that works for me for pain (inflamation). It's fantastic...except in gel form...

In pill form it works wonders (but you need to coat your stomach). In patch form (cold patch) it's the absolute best because of the targeted delivery (never seen them in the US, I buy mine in Europe OTC when I travel there or ask friends to bring them to me). In gel, it does F-all by comparison... Just a heads up, do try the pill form if possible or better yet get your hands on the voltaren patch - maybe Canada has them ?
Old 08-13-2018, 10:26 AM
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No daily pain yet, but I felt ten years younger when I moved to SWFL. There's something about the warm and humidity that effects my joints.

Likewise the cold and dry of the North are not your friend.

Anyone use a sauna with success?
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Old 08-13-2018, 03:29 PM
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Inflammation

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Originally Posted by IROC View Post
I am starting to agree with this. I actually see these Crossfit people and cringe as I bet a lot of them are going to suffer in a couple of decades. You can't tell them that now, though.

Thanks for the responses. It's somewhat comforting to hear that I am not the only one... My wife tried to tell me it was diet related and that eating "anti-inflammatory" foods would solve the problem. Not that simple...

My current worry is that everything I do is taking more life out of my joints. OTC pain meds still help, so that's where I am right now. The orthopedic doctor prescribed Celebrex, but my insurance refused to pay for it (and it was not cheap).
Your wife may be on to something. Have you tried turmeric? Turmeric has been shown to help reduce inflammation and improve joint health. The problem is that turmeric is not absorbed well unless the supplement is enhanced in some way. Look for turmeric that uses hydro-soluble technology to help it absorb better.
Old 08-15-2018, 01:25 PM
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Originally Posted by BMWz34me View Post
Your wife may be on to something. Have you tried turmeric? Turmeric has been shown to help reduce inflammation and improve joint health. The problem is that turmeric is not absorbed well unless the supplement is enhanced in some way. Look for turmeric that uses hydro-soluble technology to help it absorb better.
I don’t have any inflammation. Just joint degeneration...

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Old 08-15-2018, 05:59 PM
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