[Skytrooper]

I did this drive back in April. It is a long drive. If I remember correctly @ 8 hours. We spent the night in Penrith to break up the drive. Driving on the left is not that difficult. Like anything else, it does take time to get used to, but if you start in Glasgow by the time you get to London you will be more experienced. Pay close attention to the road signs and roundabouts...and the other traffic entering and exiting.
I have driven in UK and Scotland several times. Our trip in April was my daughters first time driving on the left. As a matter of fact she hadn't driven anything in the prior 4 months. The first hour was interesting to say the least, but she warmed up to it quickly. Of course she has applied to Oxford and Edinburgh for her Masters program. So, I am sure to be driving over there again.

Have a great time ! We love it over there !

The train would be an excellent mode to transport between the cities. Just get a car if you need to for sightseeing. The road from Inverness to Fort William however can prematurely age you, depending on the size of car you have. It is a beautiful drive. Driving from there to Glasgow through the mountains is interesting to say the least.