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I appreciate the replies.
Now after more vet evaluation it turns out he's atypical cushings- trilostane (vetoryl) appears to be working based on ACTH testing, but he remains symptomatic. Some hair loss continues, seems hot, and he's drinking a lot of water. And now has a secondary skim infection as his immune system is compromised. Water leads to late night pee time, having 'accidents' etc.
Next step is to go to a different drug, Lysodren, that directly affects the adrenals. Have heard that it has been used to go from Cushings to Addisons, with the idea being that Addisons is easier to manage. Probably more aggressive than we'd like to go.
Through it all he has remained good natured.
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