I went scorched earth with ad-blocking..
Had used U-Block and others but the my inner geek became interested in...
Pi-holeŽ Network-wide Ad Blocking
Also stopped using Firefox or Chrome... and now use Brave... which is a Chrome based browser with in built ad blocking..
With my set up some sites are broken, or you still see the space where the add was supposed to be, and its blank..
It doesn't block adds on YouTube though... supposedly they are served in a different way.. which I don't understand...
If you you have a Raspberry laying around you can make a Pi-hole and have it configured in less than an hour..