[tevake]

Tevuren's got a strong point there.
The last time that F1 tried to race at Indy's combination oval/ road course, only a few teams were able to compete in the race.

"2005, only six cars competed in the race due to problems with tires supplied by Michelin. The cars using Michelin tires withdrew from the race after the formation lap, leaving only the six cars that competed on Bridgestone tires to run the race."

If I remember correctly the drivers also were on the brink of passing out with the sustained G loads experienced in the long sustained high G turns at Indy, that did in the tires.

I wonder if the Indy cars were racing on the same course there at Indy in those years, and if so how the lap times compare?

With the amazing areo developments in F1 ( thanks Won and Capt Ahab )
It might require fighter pilot like G suits for F1 drivers to manage the loads imposed on them by the performance of modern F1 cars at a track Like Indy.

Cheers Richard