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Chloroquine is a bum fock simple drug..... it works by simply slightly changing the pH ( acidity). of small vesicles inside the cell. these are the macro-pinocytic vesicles that bud off the membrane and carry virus ( or the malarial parasite) inside the cell.... when the pH is changed, the vesicle cannot unload its contents into the cell for infection to occur. so eventuially, the contents of the vesicle are degrade, or just routed back outside the cell.
So Cq does not kill the virus, and in fact does not limit binding to the cell or internalization of the virus. It simply inhibits delivery of the virus to the cytoplasm. its is not therapeutic at all, just preventative
problem is that, for it to be effective, you must maintain a reasonably constant level of cq in the bloodstream, meaning constant , consistent dosing.
BTW. it was developed from quinine pills during ww2. also, you can got a reasonable dose of quinine by drinking gin!
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