[tdw28210]

Originally Posted by tadd

tdw:
Not quite that simple. Your analogy implies that the object used works. It would be apples to apples if we had a bunch of 'out of date' proven medication to give.

What chloroquine is is unproven. It acidifies vesicles, thus possibly slowing COVID transport into the cell. It also causes a variety of other side effects when it does that.

I'm all for last ditch trials. If you are crashing and are on deaths door, give it a shot. Just so long as everyone understands its a hail mary.

The halls of big pharma are littered with drugs that looked promising on the lab scale testing but eventually showed non-stastical effect.

Hell, read the fine print on some of the FDA approved drugs on the TV. The read the botox migraine add last night. Says it can save you one migraine a month assuming you have 15 or more. THAT is approved, so the bar isn't high.

Look at what happened to the COX-2 inhibitor. Less than 1000 people had heart attacks out of hundreds of millions of OTC doses... how did that work out?

Don't agree. "Doesn't work" runs counter to actual clinical research done in places like France and soon to be NYC and India. Is it the double-blind, randomized gold-standard? No, but were in a fox hole here. Have credible researchers provided evidence of efficacy? yep.