Quote:
Originally Posted by 93nav
"No Evidence of Rapid Antiviral Clearance or Clinical Benefit with the Combination of Hydroxychloroquine and Azithromycin in Patients with Severe COVID-19 Infection"
French study.
There is a link to a short PDF at the bottom of the webpage.
In summary, despite a reported antiviral activity of chloroquine against COVID-19 in vitro, we found no evidence of a strong antiviral activity or clinical benefit of the combination of hydroxychloroquine and azithromycin for the treatment of our hospitalized patients with severe COVID-19. Ongoing randomized clinical trials with hydroxychloroquine should provide a definitive answer regarding the alleged efficacy of this combination and will assess its safety.
https://www.sciencedirect.com/science/article/pii/S0399077X20300858 |
“There were 7 men and 4 women with a mean age of 58.7 years (range: 20-77), 8 had significant comorbidities associated with poor outcomes (obesity: 2; solid cancer: 3; hematological cancer: 2; HIV-infection: 1).”
How can they write a paper and make conclusions with such a small sample?
The original study from Marseilles had 72 patients if I recall correctly.
Statistically, this study is meaningless.