[tdw28210]

Originally Posted by Aurel

“There were 7 men and 4 women with a mean age of 58.7 years (range: 20-77), 8 had significant comorbidities associated with poor outcomes (obesity: 2; solid cancer: 3; hematological cancer: 2; HIV-infection: 1).”

How can they write a paper and make conclusions with such a small sample?
The original study from Marseilles had 72 patients if I recall correctly.
Statistically, this study is meaningless.

OK, this is almost comical. 90% of the participants (all 11 of them) we're ALREADY using oxygen because of COVID-19? And almost half them had Cancer (solid tumor or blood-borne) or AIDS? Did they forget to test it on the the guy who was being treated for gangrene? Talk about stacking the deck.


There were 7 men and 4 women with a mean age of 58.7 years (range: 20-77), 8 had significant comorbidities associated with poor outcomes (obesity: 2; solid cancer: 3; hematological cancer: 2; HIV-infection: 1). At the time of treatment initiation, 10/11 had fever and received nasal oxygen therapy. Within 5 days, one patient died, two were transferred to the ICU. In one patient, hydroxychloroquine and azithromycin were discontinued after 4 days because of a prolongation of the QT interval from 405 ms before treatment to 460 and 470 ms under the combination. Mean through blood concentration of hydroxychloroquine was 678 ng/mL (range: 381-891) at days 3-7 after treatment initiation.