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Originally Posted by jyl
They can speed things up. For example, they can do challenge trials - inoculate 5000 volunteers with vaccine or placebo, then intentionally infect 100% of them with SARS-COV-2. Ethical issues of course, but they could probably find 5,000 to volunteer with knowing consent. And of course any study participant who gets sick is promised all the HCQ they want :-) A challenge trial would be vastly faster and more powered than a traditional trial. Inoculating people and then waiting months or years for them to maybe get exposed and maybe not, or watch the trial get confounded by social distancing at some of the trial sites, I don’t think we’ll have a vaccine even in 2021 using the traditional processes.
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The virus mutates so much that a vaccine will never work, or it will be like the flu vaccine: a crapshoot that needs to be redone every year. Of course, that is every drug company’s dream, and there is a lot more money to be made than in a prophylactic drug.
And of course, just like computer viruses, new ones will emerge, either natural or man made. Bill Gates knows about that very well...
This is why we are headed into a medical tyranny of forced vaccinations, or a life of self distancing and wearing masks, unless an efficient drug is proven quickly. I had big hopes on HCQ, and it may not be the silver bullet it was touted to be, as more studies unravel. Up to the next then.