[Porchdog]

My wife constantly gets it when she weeds around the house - she refuses to wear gloves.

It's not unusual to not get it on the palms, inside of the fingers - tougher skin is more resistant.

If you think you have been exposed your best bet is to rinse with cold water, no soap. Warm water and soap help the oil to "soak in".

I'm extremely sensitive to the stuff and I can spot it right away.

Calomine is the traditional treatment - it doesn't do much for me. There are some OTC remedies that seem to help with the itch and shortening duration - There will be a dozen or so at the pharmacy.