[jyl]

Originally Posted by Aurel

I wish they would sell HCQ and zinc sulfate pills or inhalers at CVS...prevention and self medication could help many folks, and the positive studies are around. Here is one I just read:

https://www.medrxiv.org/content/10.1101/2020.05.02.20080036v1.full.pdf

Yeah, that is a retrospective open label study, not a randomized placebo controlled trial, and they had to data-mine and "adjust" to find the hint of an effect.

Compare to large RECOVERY trial in UK, which was a large randomized blinded placebo controlled trial. 1561 pts on HCQ vs 3155 on placebo, both arms also on standard of care. 27% on HCQ died in 28 days vs 25% on placebo, 59.6% discharged in 28 days vs 62.9% on placebo, 30.7% on HCQ ended up on ventilators in 28 days vs 26.9% on placebo. HCQ failed on every measure and it actually hints like it might be harmful.