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Originally Posted by jyl
Yeah, that is a retrospective open label study, not a randomized placebo controlled trial, and they had to data-mine and "adjust" to find the hint of an effect.
Compare to large RECOVERY trial in UK, which was a large randomized blinded placebo controlled trial. 1561 pts on HCQ vs 3155 on placebo, both arms also on standard of care. 27% on HCQ died in 28 days vs 25% on placebo, 59.6% discharged in 28 days vs 62.9% on placebo, 30.7% on HCQ ended up on ventilators in 28 days vs 26.9% on placebo. HCQ failed on every measure and it actually hints like it might be harmful.
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Yes, the RECOVERY trial with 3-4x HCQ doses that most true experts recommend, that one.