For those interested in historic experiences with vaccines related to "roll out,"
You may find this interesting:
https://abcnews.go.com/Health/covid-19-vaccine-rollout-compares-smallpox-polio-past/story?id=75489514
I did not previously know about the "Cutter Incident."
I think I remember consuming that sugar cube.
For more:
see also, e.g.,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383764/
And I quote:
"The Cutter incident had an ambivalent legacy. On the one hand, it led to the effective federal regulation of vaccines, which today enjoy a record of safety `unmatched by any other medical product'. On the other hand, the court ruling that Cutter was liable to pay compensation to those damaged by its polio vaccine—even though it was not found to be negligent in its production—opened the floodgates to a wave of litigation. As a result, `vaccines were among the first medical products almost eliminated by lawsuits'. Indeed, the National Vaccine Injury Compensation Program was introduced in 1986 to protect vaccine manufacturers from litigation on a scale that threatened the continuing production of vaccines. Still, many companies have opted out of this low-profit, high-risk field, leaving only a handful of firms to meet a growing demand (resulting in recent shortages of flu and other vaccines)."
Even CDC gives historical perspective:
https://www.cdc.gov/vaccinesafety/concerns/concerns-history.html
Vaccine business = "challenging"
With vaccines, drugs, devices and equipment, there are a lot of regs. I have witnessed about 40 years of evolution with respect to the latter two categories.
And I have worked with a lot of lawyers...
If I recall correctly way back when I was working for a large company that made and sold CAT scanners we were part of a lawsuit that I think asserted that our machine's x-rays caused a psychic to "lose her abilities."
PITA... but "Nothing comes amiss so money comes withal." (Grumio)
Anyway, I now have even more respect for the two people I know that are vaccine industry veterans.