https://pharmaceutical-journal.com/article/feature/everything-you-need-to-know-about-the-covid-19-therapy-trials
Latest:
On 20 July 2021, Japan became the first country to grant full approval for the use of Regeneron’s casirivimab and imdevimab antibody cocktail to treat patients with mild to moderate COVID-19;
Among patients hospitalised with severe COVID-19, treatment with canakinumab, compared with placebo, did not significantly increase the likelihood of survival without invasive mechanical ventilation at day 29 (Caricchio et al, 20 July 2021);
On 19 July 2021, the EMA announced that it had started evaluating an application to extend the use of Kineret (anakinra) to include treatment of coronavirus disease 2019 (COVID-19) in adult patients with pneumonia who are at risk of developing severe respiratory failure;
Among outpatients with SARS-CoV-2 infection, treatment with a single dose of oral azithromycin compared with placebo did not result in a greater likelihood of being free of symptoms at day 14 (Oldenburg et al, 16 July 2021).
Everything you need to know about the COVID-19 therapy trials
There are thousands of clinical trials investigating treatments and preventative measures for COVID-19.
Antivirals:
Remdesivir
Chloroquine/hydroxychloroquine
Amodiaquine
Artesunate
Lopinavir/ritonavir combination
Favipiravir
Ribavirin
EIDD-2801
Niclosamide
Nitazoxanide
Oseltamivir
Ivermectin
AT-527
Immune modulators:
Dexamethasone
Hydrocortisone
Convalescent plasma
Budesonide (inhaled)
AZD7442
Azithromycin
Doxycycline
Interferons
Tocilizumab
Sarilumab
Regdanvimab
Canakinumab
Anakinra
Baricitinib
Ruxolitinib
Tofacitinib
Acalabrutinib
Imatinib
Brensocatib
Ravulizumab
Namilumab
Infliximab
Adalimumab
Otilimab
Medi3506
Monoclonal antibody cocktail
Bamlanivimab (monotherapy)
Etesevimab (monotherapy)
Sotrovimab
Leronlimab
Risankizumab
Lenzilumab
IMU-838
Other or multiple mechanisms:
Colchicine
Dimethyl fumarate
Angiotensin-converting-enzyme inhibitors/angiotensin II receptor blockers
Statins
Aspirin
Clopidogrel
Anticoagulants
Bemcentinib
Omeprazole
Famotidine
Zilucoplan
Ascorbic acid/vitamin C
Vitamin D3
Aviptadil
Tradipitant
Nitric oxide
Fluvoxamine
Proxalutamide
Ruconest
TRV027