You might be able to if you are patient enough and look at multiple sites. I just saw a 2016 base model at Carvana with 72K miles at 36k plus taxes and fees.
https://sfbay.craigslist.org/sfc/ctd/d/san-francisco-2016-porsche-cayenne/7438406356.html
If you want to deal with private parties, you might just find a 2017 with less than 50k miles.
I sold my 2011 Cayenne S but loved every minute of owning it. But I didn't drive it much during the pandemic...