So, Manually adjust or use the smoothing function on the VE table editor. I manually toggle. Shortcuts are arrow keys to toggle across the table. Then shift+ arrow key (up/down) (or on a mac “<” and “>”) to add or remove fuel in 1 increment or ctrl+shift+arrow to change fuel in 5 increments. The adjusted cells will have a yellow tick mark on them. Here is my manually smoothed map. Notice I do not adjust a single point in the map. The fuel calculation will always use the 4 closest points and weigh them. So if there is a local high (or low) spot you want to average over that area. For example, a single low spot would be increased and then the neighboring spots would be decreased. I am sure you get the idea. In the picture below the manually smoothed bins are marked with a yellow dot. If you compare the two graphs you can see how transitions are smoothed, holes filled and peaks reduced. Ultimately you want the car fuel table to look like a very smooth waterfall.
Now you can save and load this in the car. Once you go through this a couple times it will take you just 2-3 minutes for the entire process. So, drive and datalog. Focus on one section at a time. Stop in a parking lot. Analyze. Reload. Repeat.
Next, if you want to lean or enrich an area. Change the AFR target value and run the analysis. It will automatically update in that area and you can upload a new tune to the car quickly.