I'll pop this in here just to add to the Saint Bernard content. Daisy is our fourth Saint, she's going to be 8 this year. We love our current vet and find her costs pretty reasonable. Daisy did have a four-day stay at an emergency vet hospital last winter that was good for a $5k bill - saved her life though and diagnosed Atypical Addison's which had been causing fits in diagnosis for a few months. She's on a low-dose prednisone script from our vet, and I think she charges us less than what we'd pay for a human script - a 60-day supply directly from our vet sets us back a whopping $13. She had dropped to 125lbs but is now back at her prime weight of 145lbs.