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PDF is native in OSX...from ANY application. Click print, and when the dialog box comes up there is a button for "save as pdf". So you can use any software you want and output a pdf...no need for Acrobat.
For page layout, Word in a pinch. You can use Keynote (Apple's version of PowerPoint) as it has pretty good layout capabilities (especially for text). I use Photoshop or GraphicConverter or OmniGraffle for page layout depending on what I need to do.
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