The Gold Cup was designed as a competition/target type gun. Are there better 45s for home defense? I guess so, but I'll bet sights don't even come into play when the real situation happens. You want a gun you can intuitively point and shoot well, regardless of whether you have blades, ramps, slots, laser, glow in the dark heat seeking....uh wait....anyway, that said-I think a Gold Cup would be a great defense gun-if you're comfortable with it.
I really think people get waaaay too caught up in the latest, greatest stuff. Know your gun. Practice with it. You'll be way ahead of the next guy. Who would you rather face-some punk with a 23 round Glock or some old-timer with the sights filed off his 38? I know which one would make me foul my trousers.