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I'm using Entourage but only for the calendar functions as we are on exchange. Works great for that. It is *not* a great email client if you have large email stores. I use the Apple mail client for that and aside from some minor quibbles, it has been fine. I have a TON of email too...stuff going back about 10 years.
The only compatibility issue I've seen concerns video usage between platforms, and that is often traced to not having the right codec to play the video. Also, the new version of Office on the PC side uses and XML spec that doesn't play well with anything else. Translator/filters are being worked on to deal with that, but I have yet to find anyone that has that version. The next version of Office for Mac will not have any issues. And most people who use both platforms say that the Mac version of Office is actually more elegant and better designed than the windows version. In part because the Mac business unit "gets it". Much to the chagrin of other parts of MS...
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