Fender makes the VG Strat that has Roland effects for tones and alternate tunings built in. Haven't tried one, but it could be interesting.
http://www.fender.com/vgstrat/home.html
Fender and Roland® team up once again to bring you the revolutionary new VG Stratocaster guitar.
It’s an incredibly versatile instrument that gives you 37 different Stratocaster, Telecaster®, humbucking, 12-string and acoustic sounds, plus five alternate tunings, all at the simple flip of a switch or twist of a knob. It all comes in the gracefully familiar form of an American Series Stratocaster, and it’s designed to deliver each sound with level, balanced tone and volume—no need to readjust your amp settings with each change in guitar sound.
It’s a classic Strat® in every sense of the word, with a lot of extra magic, too. For more info, visit our new Fender VG Stratocaster website.