The drive past Monterey to Big Sur is one of the finest pieces of road in America. I'd reserve a couple of hours for that.
Here's a link to the Monterey County
wine map. Other than
Chalone EDIT: Calera (world class Pinot Noir), I really don't have any direct experience with anyone there.
+1 on Ridge; Testarossa in Saratoga/Los Gatos is worth a trip; Mt. Eden in Saratoga
Have fun and let us know what you liked!