[azasadny]

You need to reboot the PC as soon as you see the screen popup, closing the browser usually doesn't work as the program brings the screen to the forefront and will not (usually) allow you to select another screen (like the browser). You can try Task Manager and shutting down the browser, but that usually doesn't work.

Once I clean the malware, I install Microsoft Security Essentials from the Microsoft website (it's free) and I keep it updated and I make sure that there aren't multiple anti-virus programs running on the PC. I then install Secunia PSI, which helps you keep all programs and components up-to-date on your PC, not just the Microsoft applications.

I've seen this malware sneak by most current A/V software, but Microsoft Security Essentials does a pretty good job of stopping it. I stopped using Internet Explorer because I believed it was less secure than FireFox or Chrome, but all browsers are susceptible to malware. I keep all Windows components and applications up-to-date on my PC's, but the malware can still hit.

If you think (as I used to) that you can avoid malware by simply avoiding "bad" websites, then you're wrong because the McAfee website was unknowingly serving up malware not too long ago and people's PC's were getting infected by simply visiting the website.

I hope this helps...