You could certainly easily kill someone with a skull crusher bezel, but nowhere is it written you have to nail someone as hard as you can in the temple either.
A good wallup to the mouth though, it would knock out several teeth and create a nasty series of deep gashes. I suspect that a good crack in the nose would cause immense non lethal damage as well.
I've pepper sprayed a lot of people over the years, so far it's worked every time, but they say some people are immune to it. No one is immune to getting their teeth knocked out.
I have a skull crusher on my AR as well. Some people get flash hiders on their home defense pistols with integrated skull crushers nowadays too.
Again, it doesn't look like much, but the skull crusher on that is made of ordnance grade steel, it's extremely strong, and very sharp.
A skull crusher on a home defense pistol or any defensive long gun is an idea with merit in my opinion.
My AR in a past configuration. I guess the bayonet does make the skull crusher a bit superfluous...