Yeah the popups can be a pain, sometimes when you close one, 3 more showup. So I have found a better way to fight them without having the trouble of aiming your mouse. It is called the (alt)- F-4 keystroke. Here is how it works. When you get a popup, While holding down the alt key, tap the F-4 key and the popup will be deleted. You can fight the popups as soon as they show, and they will disapeer as fast as you can use the keystroke.
Caution: Make sure that you are fighting the popups because you can delete the page that you were looking at if you get carried away. Have Fun