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I googled fPSA and got this explanation from Dr Catalona, an expert on the topic.
Tyrone from att.com at 12:15pm ET
Can you discuss the "free" PSA test and what it can tell a doctor?
Dr. William Catalona at 12:18pm ET
The "free" PSA test is useful in men who have total PSA values of 2.5 to 10. In these men it is difficult to determine whether these mildly elevated PSA levels are due to prostate cancer or benign causes. The free PSA test allows a more accurate prediction of whether cancer is present or not.
**** If the free PSA is greater than 25%, then there is only a one chance in 12 that cancer is present. In contrast, if the free PSA is less than 10%, then there is nearly a 60% chance that cancer is present. The free PSA also indicates how aggressive a cancer may be — the higher the free PSA, the less aggressive, and conversely, the lower the PSA, the more aggressive.
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