It depends if you want to talk tracks or full disks.
I agree that it depends on mood (esp. full disks) but Pulse or Animals are probably the best overall to me.
For track favorites:
- One of These Days
- Us and Them
- Sheep
- Comfortably Numb
- Learning to Fly
- On The Turning Away
- Keep Talking
Imho, Comfortably Numb is the greatest guitar solo of all time
I do also really like some of the covers of Pink Floyd disks and tracks:
Col. Les Claypool's Fearless Flying Frog Brigade: Shine On You Crazy Diamond (Jack Irons version) http://www.youtube.com/watch?v=_La1DckEggA
- This is the great bass player & leader of Primus and his jam band doing a version that combines the bass line from "One of these Days" with "Shine On..."
Luther Wright & The Wrongs: The Wall
- This is the entire disk of The Wall performed Bluegrass style. I know this sounds like an odd combination, but it works.
http://www.youtube.com/watch?v=6e2etT1Gtrw
(of course, "We Don't Need No Education" has a bit of a different slant when sung country-bluegrass style ;-) )
Austin Lounge Lizards: Brain Damage
- Also in Bluegrass style, and it is a hoot!!!
http://www.youtube.com/watch?v=Q75qJ3vCmBw
(Fyi, the Austin Lounge Lizards have some prog. rock era/Pink Floyd "cred" as they were formed in the late 70's by 2 Princeton History majors and a philosophy major from U of Georgia)