I was on lipitor for a while, but felt that created a problem with lack of energy. Since then, I've been on Zocor (Simvastatin) for many years. It's hard to do a comparison, but the very action of these drugs is going to cause some side effects as described. Its whether the higher levels of cholesterol are more important then the side effects. Since being on it, my levels have been in the low 100's and all the good and the bads at levels below the norm. I also take 2800mg of fish oil and COQ10 200mg along with D3. My dad, who is still living in his 80's, had bypass surgery in his 50's so its in my history. I would rather risk some fatigue and other side effects rather then a bypass any day. I still do everything I can and run 10-15 miles a week. Can't say I still don't feel tired at the end of the day but I chalk that up to turning 50
. If you can go off them and still have good cholesterol levels, do it. Just make sure you keep them checked.