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Latest, "confirmed," information.

Thailand reports it's radar picked up the left turn of the plane, supporting the claim of the Malaysian military. That would tend to lessen the likelihood the plane took a northern route (my conclusion.)

Investigators claim the turn was programmed into the computer "at least 12 minutes before" the pilot spoke the last words. That tells me two things. One, the only way investigators could make that claim is if the turn program was reported to the ground via the ACARS report at 1:07 (that's exactly 12 minutes before the last words.). Two, the turn program could have been made at any time from take-off to 1:07, and for any number of reasons, some of which are not necessarily suspect, but not reported until 1:07, and not executed until 1:21.

The last words, "All right, good night," showed no indication of trouble. Two minutes later, the programmed turn was executed. This is the key to the mystery--what happened in those last two minutes?

Pure speculation. From 1:07 to 1:21 is fourteen minutes. That gives the pilots a window in which they could have been dealing with a "situation" they didn't consider serious enough to report, a situation that they were going through their checklist to isolate, a situation that suddenly got out of hand during the final two minutes and either required them to disable the comm. systems or the incident disabled the system. Turn is executed, the rest is unknown.