What about the automatic pilot break down on a Maylasia 777 in 2005?
Investigation: 200503722 - In-flight upset; Boeing 777-200, 9M-MRG, 240 km NW Perth, WA
I have seen a CNN expert discussion about that incident. In 2005 the pilots were able to get control of the plane by going manual. But that may not always be possible if the pilots are not sufficiently trained to deal with sudden, catastrophic, malfunctions of the automatic pilot.
Then there was the Boeing warning about a fuselage structural problem at the satellite antenna that could lead to sudden decompression, 5 months ago:
Malaysia Airlines mystery: US issued warnings over Boeing 777 'weak spot' - Telegraph
What are this boards experts opinions on this information?