Steve,
For reliability the Acura TL or any of the Acura models are extremely reliable. I have had my TL for 2 1/2 years with no issue other than a filter issue. Warranty on the cars are 4 years/50,000miles and 100,000 and 6yr/70000mile powertrain warranty.
I get as high as 31-32mpg at 80 and overall mileage of 20-21mpg. Quiet, comfortable, 280HP V6 with 6 speed trans. I have owned Honda's for a long time. These are better in every way. Resale value is great. I have leased mine and am getting signed up for a TLX today. Working on selling my current TL.