I leave mine alone on my Silverado 2010 but my wife drives me crazy, she does not use the auto function, she is constantly changing fan setting or temp especially on cold mornings when she gets in the car to start. She thinks turning the temp up will get it warmer faster, can't convince her otherwise. I've given up on that exercise.
At least when I'm driving she lets me handle the controls.
I don't mess with her kitchen and she doesn't mess with my driving.