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Rough in on the toilet is OK and the flange should be far enough away from the wall when drywalled.
You may have a tough time if you tile that wall fitting the toilet in but you don't have to tile behind the tank.
The drain for the shower may be problematic. You might want to be in the middle but a good tile guy could build a pan and slope to that if you really don't want to move it.
If the layout doesn't work for you you can always bust up the floor and move things around rather than work with another persons poor planning.
__________________
Bill K.
"I started out with nothin and I still got most of it left...."
83 911 SC Guards Red (now gone)
And I sold a bunch of parts I hadn't installed yet.
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