Back when I was younger I lusted for an IS300... And then there was this TV show (Rides?) that showed Rod Millen swapping out an engine from a bigger Lexus (GS400?).
I suppose I wouldn't mind owning an IS300 now either, but it's not on top of my list. Though if I needed another 4-door sports sedan, why not?
I'd go look at this one if it wasn't raining:
http://sfbay.craigslist.org/nby/cto/5964256454.html