[2porscheguy]

It would appear that your wife has a very strong predilection towards developing POAG just based on her immediate family history so I would say best to start early here. Do you happen to know what her current IOP measures at now? Above 21 mmHG? What about her optic nerves...are they "markedly cupped"? How thin are her corneas?

Additionally, a visual field defect will not present itself until after a fairly substantial % of the optic nerve ganglions have already been affected. Once they are "dead" they won't come back no matter how aggressive the treatment so, again best to play it safe!