Its very situational.
Everyone that isn't blind is effected by looks, but the reactions differ from person to person.
Try getting a job as a hot female when the owner's jealous wife is the one doing the hiring...
That one ain't happening. In certain professional situations, really really good looks can be an impediment to females, their looks will be distracting, and the potential employer will realize this.
Good looks combined with charisma can really help empower a skunky or weaselly guy over gullible people.
How a person carries their self is even more important than their natural "looks", the looks just help in a picture, good carriage gives presence and advantage in person even from a plain or otherwise ugly person.
The females that I am most attracted to, while a certain base level of looks is important, the real "wow" factor comes from their conduct and carriage.
Being good looking can be like driving a low to the ground car, handling is improved, but somewhere a real speed bump of a person is gonna tear you up.