[Deschodt]

Muir woods is very cool and incredibly busy on week ends so hit it during the week...
Book alcatraz in advance - if you still can. Not only is is interesting as a jail/history, it's a nice ferry ride with great picture ops. Take your rental car to treasure island 1/2 way across the bay bridge in the evening just for the sights of the city from a distance... (no toll if you turn back)
If possible book the sonoma Inn for the wine country portion of your trip, it's nicely located and very comfy little houses with fireplaces and heated pool... The sebastopol area is also quite nice and hilly for wine slightly out of the beaten path... Winery wise I'd recommend Chateau St jean with nice gardens and good wine to boot but you have choices galore...
If you feel like heading all the way to Napa/St helena, The culinary institute of america (CIA) in the greystone building is a super good restaurant without the price or reservation times of the french laundry ;-)
Lots of great hikes all over Marin county... with waterfalls no less... don't drive into sausalito unless you want to do bicycle dodging all day, take a *ferry* to sausalito from the ferry building in SFO...
I'd add a trip 2.5hrs south to Carmel/monterey area for the day/maybe sleep there, and do the 17 miles drive for its gorgeous waterfront scenery, pass by pebble beach and up end in lovely Carmel. That's plenty for a week... Warning: lots of homeless and sidewalk human turds in SFO proper...