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I my case the knees were "bone on bone", meaning no cartilage left, totally worn out. My Ortho doc gave me a series of 3 euflexxa injections over 3 weeks directly into the knees. It took about 3 weeks to totally get the benefit, which helped me greatly. Next stop is total knee replacement. The doc said, meaning squats, etc., "if it hurts don't do it".
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