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1966 - 912 - SOLD
Join Date: May 2008
Location: oak grove, OREGON
Posts: 3,193
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please drink beer and eat normal bagels!!!
No Effects of Gluten in Patients With Self-Reported Non-Celiac Gluten Sensitivity After Dietary Reduction of Fermentable, Poorly Absorbed, Short-Chain Carbohydrates
Background & Aims Patients with non-celiac gluten sensitivity (NCGS) do not have celiac disease but their symptoms improve when they are placed on gluten-free diets. We investigated the specific effects of gluten after dietary reduction of fermentable, poorly absorbed, short-chain carbohydrates (fermentable, oligo-, di-, monosaccharides, and polyols [FODMAPs]) in subjects believed to have NCGS. Methods We performed a double-blind cross-over trial of 37 subjects (aged 24−61 y, 6 men) with NCGS and irritable bowel syndrome (based on Rome III criteria), but not celiac disease. Participants were randomly assigned to groups given a 2-week diet of reduced FODMAPs, and were then placed on high-gluten (16 g gluten/d), low-gluten (2 g gluten/d and 14 g whey protein/d), or control (16 g whey protein/d) diets for 1 week, followed by a washout period of at least 2 weeks. We assessed serum and fecal markers of intestinal inflammation/injury and immune activation, and indices of fatigue. Twenty-two participants then crossed over to groups given gluten (16 g/d), whey (16 g/d), or control (no additional protein) diets for 3 days. Symptoms were evaluated by visual analogue scales. Results In all participants, gastrointestinal symptoms consistently and significantly improved during reduced FODMAP intake, but significantly worsened to a similar degree when their diets included gluten or whey protein. Gluten-specific effects were observed in only 8% of participants. There were no diet-specific changes in any biomarker. During the 3-day rechallenge, participants’ symptoms increased by similar levels among groups. Gluten-specific gastrointestinal effects were not reproduced. An order effect was observed. Conclusions In a placebo-controlled, cross-over rechallenge study, we found no evidence of specific or dose-dependent effects of gluten in patients with NCGS placed diets low in FODMAPs. Australian New Zealand Clinical Trials Registry. ACTRN12610000524099
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i was too tired to be pretty last night! |
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This study was conducted in Austrailia, with non-GMO wheat.
I would be interested to see an identical study conducted in the USA with "our" wheat.
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1983 SC Coupe 2020 Macan Turbo 1963 BMW R60/2 1972 Triumph Tiger 1995 Triumph Daytona SuperIII |
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drunk and stupid
Join Date: Jan 2009
Posts: 8,619
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Did you get the memo?
Join Date: Mar 2003
Location: Wichita, KS
Posts: 33,454
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Can I just skip the bagels?
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drunk and stupid
Join Date: Jan 2009
Posts: 8,619
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Banned
Join Date: Mar 2004
Location: Michigan
Posts: 54,057
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Quote:
Quote:
Regular beer bloats my stomach out for days, even as little as a few sips of beer can have an adverse affect for a week. However Guinness isn't nearly as bad, might be a slower fermentation process which breaks down the gluten's, I'm not sure. Could be using old world traditional grains which have not been hybridized and mutated by gamma radiation. |
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B58/732
Join Date: Feb 2000
Location: Hot as Hell, AZ
Posts: 12,313
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Great, now the availability of GF foods is going to go way down once this fad ends. Guess I'll be back to eating at home all of the time.
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ΜΟΛΩΝ ΛΑΒΕ I don't always talk to vegetarians--but when I do, it's with a mouthful of bacon. |
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I have a co-worker and loose relative that have celiac (sp?) disease - both tend to just avoid items that normally have gluten. To make a gluten-free cake, pasta, bread, etc. - they need to add a lot of fat and sometimes chemicals to make it taste as good as gluten-laden originals do. Sorry to be the bearer of bad news, but the fad isn't good for you either.
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