There is a new drug for severe gout w/ tophi. Krystexxa I think. I don't know any more. I missed the stock so I lost interest . . .
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I have seen plenty of late effects of uric acid.
When the cartilage erodes away, I have seen the defect look white, an intra osseous cyst full of it or a gouty tophus(like a big pimple or boil) that erodes through the skin. It looks just like toothpaste. It is bright white, very distinctive looking.
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