Nanoplastics In Water Bottles

[William930t]

Bill's reference above really got me thinking about the need for nano/cancer research. Google quickly found a number of initial studies, this info below is direct from a 2024 NIH report:

The incidence of colorectal cancer in those under 50 years of age (early onset colorectal cancer (EOCRC)) is increasing throughout the world. This has predominantly been an increase in distal colonic and rectal cancers, which are biologically similar to late onset colorectal cancer (LOCRC) but with higher rates of mucinous or signet ring histology, or poorly differentiated cancers. The epidemiology of this change suggests that it is a cohort effect since 1960 and is most likely driven by an environmental cause. We explore the possible role of microplastics as a driver for this change.

The development of sporadic colorectal cancer is likely facilitated by the interaction of gut bacteria and the intestinal wall. Normally, a complex layer of luminal mucus provides colonocytes with a level of protection from the effects of these bacteria and their toxins. Plastics were first developed in the early 1900s. After 1945 they became more widely used, with a resultant dramatic increase in plastic pollution and their breakdown to microplastics. Microplastics (MPs) are consumed by humans from an early age and in increasingly large quantities. As MPs pass through the gastrointestinal tract they interact with the normal physiological mechanism of the body, particularly in the colon and rectum, where they may interact with the protective colonic mucus layer. We describe several possible mechanisms of how microplastics may disrupt this mucus layer, thus reducing its protective effect and increasing the likelihood of colorectal cancer.

Conclusions: The epidemiology of increase in EOCRC suggests an environmental driver. This increase in EOCRC matches the time sequence in which we could expect to see an effect of rapid increase of MPs in the environment and, as such, we have explored possible mechanisms for this effect. We suggest that it is possible that the MPs damage the barrier integrity of the colonic mucus layer, thus reducing its protective effect. MPs in CRC pathogenesis warrants further investigation.

Future directions: Further clarification needs to be sought regarding the interaction between MPs, gut microbiota and the mucus layer. This will need to be modelled in long-term animal studies to better understand how chronic consumption of environmentally-acquired MPs may contribute to an increased risk of colorectal carcinogenes.

[recycled sixtie]

Well we all have to die of something. Excessive plastic ingestion accumulated over the years could be a new way to pass on. Hopefully legislation will prevent that happening.

My wife buys a case of bottled water. I take one when I go golfing and reuse the bottle by filling with tap water.

Edmonton tap water is excellent. Calgary tap water is not so good. Calgarians can chime in if they like! I would take our tap water over bottled water any day.

Cheers, Guy.

[Arizona_928]

Originally Posted by kach22i

I noticed something strange about the water bottle left in my car overnight - it did not freeze.

Search term: plastic water bottle not freezing


I've been bringing well water from home to drink at work (metal travel cup) for the last six months.

I seem to drink less water unless I'm making tea to keep warm.

Yawn. Take your super cooled bottle of water and add some energy (whack it ) and watch it crystallize.

[Arizona_928]

Originally Posted by William930t

Bill's reference above really got me thinking about the need for nano/cancer research. Google quickly found a number of initial studies, this info below is direct from a 2024 NIH report:

The incidence of colorectal cancer in those under 50 years of age (early onset colorectal cancer (EOCRC)) is increasing throughout the world. This has predominantly been an increase in distal colonic and rectal cancers, which are biologically similar to late onset colorectal cancer (LOCRC) but with higher rates of mucinous or signet ring histology, or poorly differentiated cancers. The epidemiology of this change suggests that it is a cohort effect since 1960 and is most likely driven by an environmental cause. We explore the possible role of microplastics as a driver for this change.

The development of sporadic colorectal cancer is likely facilitated by the interaction of gut bacteria and the intestinal wall. Normally, a complex layer of luminal mucus provides colonocytes with a level of protection from the effects of these bacteria and their toxins. Plastics were first developed in the early 1900s. After 1945 they became more widely used, with a resultant dramatic increase in plastic pollution and their breakdown to microplastics. Microplastics (MPs) are consumed by humans from an early age and in increasingly large quantities. As MPs pass through the gastrointestinal tract they interact with the normal physiological mechanism of the body, particularly in the colon and rectum, where they may interact with the protective colonic mucus layer. We describe several possible mechanisms of how microplastics may disrupt this mucus layer, thus reducing its protective effect and increasing the likelihood of colorectal cancer.

Conclusions: The epidemiology of increase in EOCRC suggests an environmental driver. This increase in EOCRC matches the time sequence in which we could expect to see an effect of rapid increase of MPs in the environment and, as such, we have explored possible mechanisms for this effect. We suggest that it is possible that the MPs damage the barrier integrity of the colonic mucus layer, thus reducing its protective effect. MPs in CRC pathogenesis warrants further investigation.

Future directions: Further clarification needs to be sought regarding the interaction between MPs, gut microbiota and the mucus layer. This will need to be modelled in long-term animal studies to better understand how chronic consumption of environmentally-acquired MPs may contribute to an increased risk of colorectal carcinogenes.

No one is funding it because it’ll crash the markets that exclusively use these products. Nature wouldn’t even entertain the thought of this topic. Imagine going back to butcher paper and glass containers for everything? How would the corporations offset those costs.

One can watch YouTube videos of people with a simple microscopes looking at the microplastics in processed foodstuff.

[cockerpunk]

Originally Posted by Tobra

Yes they are, especially fluoride

no, it still isnt.

[Arizona_928]

Originally Posted by cockerpunk

no, it still isnt.

Evidently, you’ve been drinking that halogenated water




https://www.eenews.net/articles/epa-in-a-really-tough-spot-after-landmark-fluoride-ruling/

https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/completed/fluoride

https://hsph.harvard.edu/news/fluoride-childrens-health-grandjean-choi/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3491930/

[cockerpunk]

Originally Posted by Arizona_928

Evidently, you’ve been drinking that halogenated water




https://www.eenews.net/articles/epa-in-a-relly-tough-spot-after-landmark-fluoride-ruling/

https://ntp.niehs.nih.gov/whatwestudy/assesments/noncancer/completed/fluoride

https://hsph.harvard.edu/news/fluoride-chilrens-health-grandjean-choi/

https://pmc.ncbi.nlm.nih.gov/artcles/PMC3491930/

im sorry your dusted off conspiracy theory from the mid 1950s, still does not hold water.

these are basic facts, im sorry. you are just wrong.

[Arizona_928]

Originally Posted by cockerpunk

im sorry your dusted off conspiracy theory from the mid 1950s, still does not hold water.

these are basic facts, im sorry. you are just wrong.

How am i wrong?

How is the science wrong?

[911 Rod]

We just drink tap water. I actually fill up the water dispenser with tap water in my office.

[cockerpunk]

Originally Posted by Arizona_928

How am i wrong?

How is the science wrong?

your conspiracy theory, is wrong, yes.

[herr_oberst]

Originally Posted by VINMAN

I've always said from the beginning that bottled water was rhe biggest scam.

I've always avoided it unless absolutely necessary.

.

I'm with you on this one. I've got bottled water in my earthquake stash, along with a few 5 gallon jugs, but paying Nestle corporation for what comes free out of the tap is madness to my mind. I'll just get my cancer from other places.

[Arizona_928]

Originally Posted by cockerpunk

im sorry your dusted off conspiracy theory from the mid 1950s, still does not hold water.

these are basic facts, im sorry. you are just wrong.

Originally Posted by cockerpunk

your conspiracy theory, is wrong, yes.

Fluoride is a neurotoxin…
And that’s the facts Jack

[cockerpunk]

Originally Posted by Arizona_928

Fluoride is a neurotoxin…
And that’s the facts Jack

everything is a toxin when you put too much of it in your system. you can die of drinking too much water, that doesn't make water poison.

jesus this is high school chemistry. just find a school bus, any one will do, and get on it. just take it to wherever its going.





how do we live in a world and fully grown adults, who presumably are successful humans, are full of such, absolute ****ing hogwash?

at least in 1964 we had the good sense to openly mock this conspiracy.

[Chocaholic]

Can you share a study or two that confirmed the safety of fluoride in drinking water? That might help. I have no knowledge or opinion on the subject but just proclaiming “you’re wrong” isn’t compelling evidence.

[Tobra]

Fluoride was a toxic industrial waste before they started putting it in the water

Look it up cp. We are here to shine a light on your ignorance.

You are welcome

[cockerpunk]

Originally Posted by Tobra

Fluoride was a toxic industrial waste before they started putting it in the water

Look it up cp. We are here to shine a light on your ignorance.

You are welcome

yes, i have taken high school chemistry.

this place is just full of nonsense. basic educational nonsense. we should be bullying this stuff. being gay isnt a choice, but believing in total nonsense is. that makes this fair game. JFC.

please, just go to high school, im begging you. basic chemistry isnt that hard.

https://www.youtube.com/watch?v=xQyf3QgRP-c

[pavulon]

I hope essential oil sales pick up soon...mostly because it might take up some time otherwise spent here repeating Alex Jones sorts of BS.

[IROC]

Flouride (at the levels in drinking water) is perfectly safe. Geez you guys.

[cockerpunk]

Originally Posted by pavulon

I hope essential oil sales pick up soon...mostly because it might take up some time otherwise spent here repeating Alex Jones sorts of BS.

right?

https://www.youtube.com/watch?v=LFc5hwqiJTw

its not brilliant, its just dumb.

Originally Posted by IROC

Flouride (at the levels in drinking water) is perfectly safe. Geez you guys.

we are in the year of our lord 2025, on the verge of creating quantum ****ing computing, unlocking and manipulating a universal truth so fundamental to our existence it will redefine our entire reality, and somehow, we are dealing with fluoride in the ****ing water conspiracies.

i used to think human problems were hard. they are hard things to fix. no, they are dangerously easy. so easy in fact, that somehow some subset of society gets a special feeling in their ting-a-lings, to disagree with it. its not brilliant, its just dumb.

[cockerpunk]

i recently saw a tiktok that made the argument that there has only ever been one social disagreement. throughout all of your lives, from the founding country onwards ... only one actual disagreement.

and that disagreement is "was the enlightenment a good idea or not?"