I could write a training seminar on this subject. oh wait, I already have
Answer: depends.
What metals are involved?
Similar, dissimilar?
What temperatures?
What environment (salt, moisture, etc).
Food processing or not ....
There's a reason they make about a dozen different kinds of anti-seize. NONE of them are good at everything.
That permatex bottle shown above is pretty good at most.
I wouldn't use it on a gas expander, but for most home and automotive uses it's OK.
BTW, Many formulas of anti-seize have either disappeared to have gotten weaker over the years thanks to the EPA and other regulatory jack-holes.
Lead was a good additive, but that could get on someone's skin or some idiot might use it on potable water, so that's outlawed.
Same with at least 4 or 5 other additives that were previously common.
Believe it or not one of my favorite recipes for exotic stainless fasteners in high temp applications is is high temp nickel-eze mixed with milk of magnesia.