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john70t's Avatar
 
Join Date: Aug 2001
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Tooth enamel regeneration?

It might be possible with the right toothpaste. Those kids with rotten Mountain Dew cola drinking mouths might have a chance to have natural chicklettes to show off much later on in life.
(caveat: this is something seen on the internet. I have no idea what the other ingredients do with each product..)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432723/
3.1. Tooth Remineralisation

Modern dentistry has taken a more preventative approach through the understanding of enamel remineralisation in early carious activity [17]. Demineralised enamel and dentine have mineral ions removed from the HA crystals [40]. If the HA is partially demineralised, then this process is reversible if exposed to favourable oral environments [40]. This process is called remineralisation, where lost mineral ions in the HA crystals are restored [40]. There are many methods of remineralisation, saliva can aid in remineralisation by providing a constant source of calcium and phosphate required for the process to occur [40,41]. Fluoride also promotes remineralisation by forming fluorapatite with the calcium and phosphate released from demineralisation, this is more resistant to acid attack [40,41]. Casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) is another system that promotes the precipitation of minerals to hard tooth tissue [41].

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Old 09-04-2023, 09:31 PM
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Yes you can remineralize enamel to a certain extent. Most effective with smaller incipient decay/demineralization.

If you were thinking you could regrow enamel in a 2 x 3 mm defect you would be disappointed.

I used to get free samples of a toothpaste called EnamelOn which advertised remineralization of decay. To be honest I was impressed with its desensitization effects

No affiliation but here is a link.

https://www.enamelon.com/
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Old 09-04-2023, 10:22 PM
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It sound fantastic but I'd bet it's expensive.
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Old 09-04-2023, 11:26 PM
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Quote:
Originally Posted by RNajarian View Post
Yes you can remineralize enamel to a certain extent. Most effective with smaller incipient decay/demineralization.

If you were thinking you could regrow enamel in a 2 x 3 mm defect you would be disappointed.

I used to get free samples of a toothpaste called EnamelOn which advertised remineralization of decay. To be honest I was impressed with its desensitization effects

No affiliation but here is a link.

https://www.enamelon.com/
Yes indeed. As you know well Doc remineralization has been a dream for a very long time. Desensitization however is indeed a reality. I have many years of R&D experience with brands such as Sensodyne and Pronamel.

Repairing a carious lesion just isn't possible with an OTC product yet. Any product claiming that it can do so is just lying or at the least is misrepresenting what their product can do. A dentifrice may help slow enamel loss but that's it.

What is often represented as remineralization is just the introduction of hydroxy apatite into the matrix but it does not heal a carious lesion.

There is also a little known side effect of Stannous Fluoride which is staining of the enamel. Sodium Fluoride doesn't do that.

Also, we should brush before we eat and not after eating acidic foods. Acidic foods soften the enamel and brushing can accelerate enamel wear. Instead use a fluoridated rinse after eating to restore a neutral pH.
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Old 09-05-2023, 06:41 AM
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Sensodyne and Pronamel are my #1 and #2 toothpaste recommendations. #3 is Periodontax also made by Glaxco Smith Kline.

No doubt there will be a procedure to remineralize larger lesions in the future. Likely involving several in office steps. However, I don’t doubt in 20 years there will be an OTC product available likely the result of your research.
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Old 09-05-2023, 07:30 AM
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I’m getting great results with Flex Seal.
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Old 09-05-2023, 10:31 AM
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Quote:
Originally Posted by Steve Carlton View Post
I’m getting great results with Flex Seal.
Just don’t use the black colored product.
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Old 09-05-2023, 10:33 AM
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I'm thinking of using that same process they use to refinish the enamel on cast iron bathtubs. Can I still get Avocado Green?
Old 09-05-2023, 11:54 AM
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Quote:
Originally Posted by RNajarian View Post
Sensodyne and Pronamel are my #1 and #2 toothpaste recommendations. #3 is Periodontax also made by Glaxco Smith Kline.

No doubt there will be a procedure to remineralize larger lesions in the future. Likely involving several in office steps. However, I don’t doubt in 20 years there will be an OTC product available likely the result of your research.
We also got into developing a permanent sealant as a preventative measure but it went nowhere pretty quickly.
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Old 09-05-2023, 02:19 PM
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Quote:
Originally Posted by Steve Carlton View Post
I’m getting great results with Flex Seal.
Have you tried JB Weld? It builds up quick!
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Old 09-05-2023, 03:50 PM
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Quote:
Originally Posted by flatbutt View Post
We also got into developing a permanent sealant as a preventative measure but it went nowhere pretty quickly.
When I was 17/18 (late 80s) I went to the dentist (before beginning college) and had everything taken care of. They also applied a sealant to all of my molars. I have no idea what it was or anything, but it was many, many years before I went back to a dentist, and I only had a couple/few small cavities. I don't know if that's just my genetics or the sealant or what.
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Old 09-05-2023, 04:11 PM
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Enamel remineralization. Yes

Enamel regeneration not possible.... Like the spin turbo fuel saver 😉
Old 09-05-2023, 06:01 PM
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Enamel remineralization-public fluoridation has been around in varying degrees since the 1940's

Enamel regeneration- the next big thing- right around the corner- like a rainy day homemade nuclear fusion reactor in a 1950's popular science magazine made out of a coleman cooler, plaid, and boy scout badges. Lot of cool research, and lots of potential, but nothing coming to a theatre near you in the next week or two.
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Last edited by LEAKYSEALS951; 09-05-2023 at 06:35 PM..
Old 09-05-2023, 06:10 PM
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I remember seeing a documentary about a guy who was a Re-Enamelator in 1985. I'm sure it's more advanced now.

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Old 09-05-2023, 06:27 PM
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Quote:
Originally Posted by Steve Carlton View Post
I remember seeing a documentary about a guy who was a Re-Enamelator in 1985. I'm sure it's more advanced now.


And THIS is why tooth regeneration should be STOPPED right now. Who knows where it will lead!!!
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Last edited by LEAKYSEALS951; 09-05-2023 at 06:35 PM..
Old 09-05-2023, 06:32 PM
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Must be at least 18 years old.

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Old 09-05-2023, 06:42 PM
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^ where'd you get that pic of me?
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Old 09-05-2023, 06:59 PM
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It's on the LEAKYSEAL facebook page. It said you were the 4th grade apple eating contest champion.
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Old 09-05-2023, 07:08 PM
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It's on the LEAKYSEAL facebook page. It said you were the 4th grade apple eating contest champion.
Ah hell, I thought that pic was on the "private" setting. Damn you z-berg!
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Old 09-05-2023, 07:15 PM
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Timely thread. I've been using some of the Crest Pro-health products for the past year and a half and I think they are helping with my dental health.
Crest Pro-Health Gum Detoxify and Restore Toothpaste, Deep Clean

Crest Pro-Health Densify Toothpaste Daily Protection with Fluoride for Anticavity and Sensitive Teeth

Crest Toothpaste Gum Detoxify Deep Clean
Appreciate the recommendation of the Sensodyne, Pronamel, and Periodontax, RNajarian!

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Old 09-05-2023, 08:12 PM
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