Moderna 94.5% effective

[Noah930]

Originally Posted by pmax

The 4 who got sick, was it worse ?

Originally Posted by jyl

No serious Covid cases in drug arm.

I cannot recall the manufacturer, but didn't one of the trials have a side effect which sounded like transverse myelitis? The news I read was always very vague about this. But if it was transverse myelitis, that's one of those dreaded worse-than-the-illness side effects. Super rare, but I have seen one woman who became paraplegic from something as supposedly innocuous as a hepatitis vaccine.

Edit: it was the AstraZenica vaccine trial.

[pmax]

So, no recourse if RB grows a tail ?

[red-beard]

As long as it is prehensil, I'm cool with that

[Sooner or later]

Originally Posted by red-beard

As long as it is prehensil, I'm cool with that

Increased productivity by at least 25%,

[jyl]

Originally Posted by Noah930

I cannot recall the manufacturer, but didn't one of the trials have a side effect which sounded like transverse myelitis? The news I read was always very vague about this. But if it was transverse myelitis, that's one of those dreaded worse-than-the-illness side effects. Super rare, but I have seen one woman who became paraplegic from something as supposedly innocuous as a hepatitis vaccine.

Edit: it was the AstraZenica vaccine trial.

AZN and the UK didn't disclose much about the case. The FDA has whatever data there is and has, I think, greenlighted resumption of the US trial. But there as well, no public disclosure. I am speculating that they know she developed TM and was in the drug arm and that's about all they know, can't prove or disprove that it was vaccine-caused. I've read some comments that in a trial this size, one TM case isn't going to stop it but a second would be very serious.

[pmax]

Sorry, joking aside, seriously, let me rephrase the question, is the indemnity iron clad, in the trial and in general ? Zero recourse ?

[jyl]

https://www.policymed.com/2011/03/supreme-court-rules-in-favor-of-protecting-vaccine-makers-from-state-lawsuits.html

https://theintercept.com/2020/08/28/coronavirus-vaccine-prep-act/

I'm not planning to do more than the 30 seconds of "research" represented above, but looks like little to no legal recourse unless clinical trial agreements provide remedy.

[island911]

President Trump organized and directed pulling the down road-blocks and put up massive resources to the CV problem.

https://en.wikipedia.org/wiki/Operation_Warp_Speed

Operation Warp Speed (OWS)[1] is a public–private partnership, initiated by the U.S. government to facilitate and accelerate the development, manufacturing, and distribution of COVID-19 vaccines, therapeutics, and diagnostics. Operation Warp Speed was introduced in early April 2020,[2][3][4] after a round-table meeting with industry executives at the White House on March 2.[5] It will promote mass production of multiple vaccines based on preliminary evidence allowing for faster distribution if clinical trials confirm one of the vaccines is safe and effective. The plan anticipates that some of these vaccines will not prove safe or effective, making the program more costly than typical vaccine development, but potentially leading to the availability of a viable vaccine several months earlier than typical timelines.[6] U.S. Congress allocated on March 27 nearly $10 billion for Operation Warp Speed through the CARES Act (Coronavirus Aid, Relief, and Economic Security) with $6.5 billion designated by Congress for countermeasure development through BARDA,[7] along with $3 billion for NIH research.[8]

[RWebb]

Originally Posted by Porsche-O-Phile

The goal is to get enough people vaccinated during its effective time where the number of available hosts to the virus drops to zero (or nearly to zero). At that point the virus basically dies off. At worst it would stop proliferating. That’s simplistic but that’s the general idea (I’m not an epidemiologist).

In any case, really good news. I’m very happy to hear it’s coming from a US company (and most especially not a Chinese one!)

That's the general idea. Here is an analogy:

You have a bunch of islands, with animals living on them. The islands are the hosts (us), and the animals are the virus.

The animals will die out on each island (either directly, or the island will vanish (host dies)). The trick for the virus "animals" is to disperse (spread) to a new island before the are extirpated on the existing island.

The ability to disperse to new islands is measured by R.

There are ways to prevent dispersal to new islands, such as masks, isolation, etc.

It is called the Theory of Island Biogeography and there is likely a wiki on it. Epidemiologists (of the stripe who study disease spread) learn and use this concept in their models.